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1@BarcaSource17,604
2@EWdeVlieger29,889
3@JadeJoliex25,509
4@Cuteguy__5,836
5@crisspyguy2,847
6@umarebru36,354
7@Saad49347,558
8@erlang_ehzan956
9@Avisdejoueur1,183
10@besiktasajansi10,035
11@WeesperMopper1
12@AlexMunter_22,177
13@JulietteRot2,360
14@Namenode526,500
15@fynna33631
16@quironsalud20,898
17@saaan_rina11,859
18@patrik_kara12,573
19@DragMeDownkid220
20@jahangirjahejo156,275
21@tamhonks8,886
22@iaeLuk14,998
23@MudassirMadi2,418
24@DouglasAndradde58,772
25@soenarko1,784
26@WWAYSports4,511
27@HumbertoTan970,085
28@arjenlubach211,415
29@AvadoreCo30,180
30@ALyemenNow884,042
31@yuan_ochi4,874
32@matthewsgreg146
33@name5,244
34@_EsTehHangat2,829
35@PenguinIndia151,699
36@SuzanneCordeiro80,452
37@mi_Pranay2,045
38@geertwilderspvv940,191
39@mister__marinho940
40@imkangana130
41@wectnews53,827
42@SanderBijl930
43@Cambly_AR36,104
44@ArnabGosvami252
45@MPVissers846
46@VujaBoskov67,277
47@alrahbi5256,608
48@tomjanmeeus28,057
49@MichaelvanPraag17,720
50@iAMEERMUKHTAR6,095
51@PCGamesN89,844
52@Mohammed_alshe2,055
53@sat1577,554
54@hamburgcam4,507
55@HekmahOrg101,864
56@imhitlardidi77
57@jrwingman126,327
58@PSV406,800
59@Hermaniak4,529
60@DusDavid192,981
61@Noemi4Pleasure3,183
62@Morocco22,970
63@petergraigs50,888
64@osantiagotorres194
65@surbhi_24041,230
66@DrAlfonsoVidal10,525
67@alkhandakschool1,657
68@AGATAmusic53,270
69@dutchdreamer_5,882
70@SahiDisha11,095
71@jackyeclayton12,917
72@tuistarcita32
73@USAnonymous72,303
74@infopingapp344
75@YoeriAlbrecht25,868
76@Cihanyaziyorr84,479
77@DieRehfeldt90
78@RwandaTimes3,293
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80@SarahAngius3,914
81@nuffsaidNY16,760
82@_miguelferreira1,705
83@britbeautyblog53,174
84@F_azarkan12,971
85@sstranger2,801
86@RudySnippe35,110
87@azelin35,317
88@DiariodeMorelos171,276
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90@iMiaSanMia74,297
91@elconfidencial721,731
92@BauerJup771
93@erwblo37,320
94@HunterS_Jones64,115
95@quratoffice23
96@LilKleine65,622
97@Zayn1,899
98@Aghawajid1236,333
99@gino2,180
100@DioFavatas220,120
101@AliedeVriezz484
102@iJohnyLever2,048
103@MaxMahlur21
104@YuriAnkone1,311
105@imrankhan20,294
106@TheSocialQuant107,629
107@0xBigBan620
108@dodevogels153
109@Fighting_Fifty6,868
110@musicaljournaal6,242
111@borsato909,763
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113@iSwetaSinghAT1,525
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119@EcoleduLouvre30,548
120@rnovoa3,351
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123@RankReckoneers2,042
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128@BOY2,904
129@Louis__GA101,000
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131@Giels788,371
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135@SKYFULLOFMARTIN3,052
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139@SirRajinikant18,458
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143@Catenaccio24,565
144@LindaSuhler347,218
145@Dudes4Dudes131,246
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148@Feyenoord437,149
149@thadiqonline4,071
150@PSSleman155,486
151@almasdaronline648,872
152@Redfive05ive1,216
153@karantacker970,623
154@sylviawitteman157,293
155@TopTdawl4,750
156@FrontaalNaakt8,690
157@JutWare2,842
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159@StopKidnaping1,337
160@Manilanazzaro6,466
161@MoniqueAdriaan12,030
162@imkanganaranut4
163@kidswowenglish1,058
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165@TabberAnn2,423
166@NikkiTMB4,395
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170@KhrystalKDavis25,626
171@mzaji_rayeg22
172@MKutney123,207
173@sami876
174@miquelrius_es1,257
175@Arad_Online106
176@ABUnl7,259
177@WoJiaoWeiLin337
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182@khabaragency273,367
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184@yemen21,969
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186@TedRubin534,704
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188@marievlundvall28,541
189@Footballogue920,634
190@SnowinRI97,457
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192@DominaSreni1,502
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195@Toner_Low38
196@vrij_nederland71,704
197@selvaorejon8,621
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199@Wiswijzer2488
200@ArleneDickinson314,103
201@PS_JBrownXXX41,205
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203@Dutchtuber108,047
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205@Sandernop2,217
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207@carlosainz77
208@Max33Verstappen744,614
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214@austinnotduncan401,459
215@Fliktwit740
216@Noud4,643
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220@kx3036,708
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224@gm7uniformes342
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226@AnimeLandbta500
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228@Jenka_Tanny2,967
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231@Race_Inc440
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233@guidovanvliet26,934
234@Bo_ytk231
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236@The_Ruhi1,043
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250@pewe63794
251@douwe_bob46,971
252@LiLa1,590
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254@xSultan1871,908
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256@karoseriID15,561
257@evawesterhoff3,444
258@DeLaMoutarde281
259@DITenergie1,482
260@BeingKangna2
261@FX_Digital248,219
262@deieio131
263@Dorest0rm739
264@MSamplonius73
265@BlessedAtWorld491,180
266@gelipetv6,889
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268@kannebree145
269@Naive_10Year123
270@openomroep6,187
271@RRankinFans9,604
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273@_letlarrylove875
274@marcvanderstelt3,512
275@SwanTheVoice9,079
276@Malabares226
277@luxulmusic4,929
278@pirathygrrr1,764
279@ChielSpot682
280@ashatenbroeke13,239
281@SaudiMOCS1,187,713
282@rafacst20,316
283@SG_Nicholls2,018
284@SuperRewinder273
285@phuquoc_in9,277
286@RobTigerius142
287@prakashcena96558
288@Kesit_267
289@AustinAyyub11,511
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291@AFCAjax913,736
292@Pihlblad38,138
293@ahope7135,324
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295@StussyTheGoat485
296@IelloUSA19,317
297@dklaheaven3,021
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299@DJ_Russia296
300@A_z0li1,330
301@markosuomi12,771
302@jxymn2,071
303@irishlck581,324
304@Ali_Albukhaiti924,640
305@camslurrr291
306@jobs2saudi87,898
307@allcinemanews4,393
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310@3zozE545
311@12be9fb42e744d4207
312@jaspro101423
313@SecretosdeMadri714,513
314@TunezUnknown68,437
315@AXA69,012
316@ADAGIO_TV33,443
317@eurogamer350,770
318@CeciliaStok802
319@spunkymunkeymus76,509
320@AnthonyHopkins149,811
321@bibiletal972
322@__Neetu_8,165
323@mathieuvanlinde1,225
324@OnSeFaitChier3,893
325@jaanjahejo104
326@ScentedVapors1,536
327@ClaireeBear95458
328@ammarodehonline6,555
329@SAT1_Gold2,442
330@SirManojBajpai109
331@Yemen_Brk303,351
332@Yeroen899
333@arunmsrr7,400
334@kellymay9570
335@metkennisvannu1,232
336@Jahejo5,916
337@iSunnyDeol208
338@Farah2,466
339@eliflelik101
340@TheRealTRizzo127,024
341@iot944
342@loyyang28468
343@UltChart7,608
344@PaulineMeijer31,371
345@Day1,988
346@lalatimepass6,755
347@malrowily666394
348@iRaviSharma91,884
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350@HankyFacts3,943
351@SirSunnyDeol3
352@ibrahimvbz1,125
353@pcinvasion17,866
354@mo3enmane3608
355@Muntpunt5,904
356@IAmJohnSparks312,268
357@billbelew_com83,653
358@JonasFlorinus120
359@N_binakdemees1,320
360@NasAsim916
361@youssef__ramy738
362@mvno1,012
363@USCERT_gov76,482
364@mirjamdj753
365@SouqKuwait32,793
366@ThEsAiV5,617
367@abakker28416
368@Twisted_Shadow1,160
369@winnieardiana12,498
370@promo_kredit40
371@wrdknstnrs1,199
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373@darkrain_nl256
374@Podcast2,180
375@Chrissyfied86239
376@M1st3rW4nt3d289
377@VeryBustyAsian635
378@GeertMilder22,988
379@mrtsoft1,844
380@Magister_7167
381@marebpress882,404
382@ebayindia237,952
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385@SirSunilShetty37,273
386@SorumsuzHerif96,635
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395@Sadaka_111409
396@MF9046110,968
397@obnoxiousEm51
398@Ceilidhann7,422
399@Iocationdolan57
400@8teendoIan51
401@mr_brroo2,870
402@BellaMiss8226
403@PabloExposito769
404@SaadAR1432248
405@DanieTreg12,163
406@hi6yuqui25,208
407@nanarosegmail657
408@castienk59,457
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415@asadali123_6,526
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417@hassanalishah_6,300
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420@nangineeta6,305
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423@SGOMEZFECT102
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427@mathpaul964
428@realhollowloop2,977
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433@khin0r85svg12
434@dickdigdick26,385
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Martyn Pickersgill @PickersgillM
My excellent @EdinUniUsher colleagues @sarahwchan, @DrEllenStu & @ingridkyoung are recruiting fully-funded PhD students, who'll be associated with our @EdinburghUni/@wellcometrust 'Biomedicine, Self & Society' initiative: findaphd.com/search/Project… #STS #sociology #socsci #bioethics
8 Dec 2017               
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Martyn Pickersgill @PickersgillM
.@EdinburghUni will be supporting @Sarah_C_Burley, @sarahwchan, @GillHaddow, @GraemeLaurie, @devisridhar, @stevesturdy & I to develop a new Centre for Biomedicine, Self & Society, following a £1m @wellcometrust award: ed.ac.uk/usher/news-eve… #socialscience #medhums #globalhealth
8 Dec 2017               
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Steve Joffe @SteveJoffe
@charlesweijer @AlexJohnLondon @SG_Nicholls @SpencerPHey @coryegoldstein I don't mean to be an unreasonable skeptic. Entirely plausible that significant response is tightly assoc w ⬆️ QoL in many cases so long as toxicity of drugs doesn't outweigh. But as w any surrogate, must demonstrate relationship to clinically meaningful outcome.
7 Dec 2017 in reply to charlesweijer               
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Charles Weijer @charlesweijer
@AlexJohnLondon @SteveJoffe @SG_Nicholls @SpencerPHey @coryegoldstein Excellent thread! I agree with @SteveJoffe. Are mechanism/ outcome being conflated? Tumour shrinkage seems valuable when it improves symptoms/ QOL/ survival, but not valuable in itself. This suggests it not the relevant outcome but the mechanism.
7 Dec 2017 in reply to AlexJohnLondon               
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Steve Joffe @SteveJoffe
1/ @UPenn_MedEthics is accepting applications for two postdoctoral fellowships in #bioethics. …dicalethicshealthpolicy.med.upenn.edu/in-the-news/po…
17 Oct 2017               
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Steve Joffe @SteveJoffe
Shared control arm for a multi-arm multi-company trial is great. Getting companies to collaborate will be the challenge. And DSMB questions could be hard. But right thing to do for kids.
U.S. FDA @US_FDA
Working w/ EMA, FDA has drafted an approach to pediatric rare disease drug dev that could eliminate need for certain clinical studies & when studies are needed, could reduce # of patients who would receive a placebo instead of a potentially helpful drug go.usa.gov/xn58P
7 Dec 2017               
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Sonya de Laat @SonyadeLaat
Come to listen. Come for discussion. Come for the cookies. #aidethics #researchethics
Lisa Schwartz @LisaSchwartz224
Global Research Ethics: Experience in disaster contexts
@MHuntMcGill @SonyadeLaat @HumEthNet on experiences and learning about how research ethics can be done in global humanitarian settings @McMasterU MDCL 3022
Time: Thursday December 7, 3-5pm
humanitarianhealthethics.net
7 Dec 2017               
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Steve Joffe @SteveJoffe
I'm all for patient-centered outcomes but also believe beneficial-->improves length or quality of life. Is the fact that pts say response or delaying progression is valuable sufficient to conclude that those outcomes improve quality of life?
FDA Oncology @FDAOncology
We heard from patients that response rates--shrinkage of tumor of sufficient magnitude and duration--as well as delaying progression of a life-threatening disease is valuable to them- Pazdur #SABCS17
7 Dec 2017               
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Charles Weijer @charlesweijer
#Cost is an important #barrier to #participation in #cancer #RCTs. "50% of respondents cited out-of-pocket costs as a reason not to enroll in clinical trials." @BeverlyMoy @yzafar @ASCO @AmericanCancer @CCS_Durham @CBCF
Anne-Marie Baird @BairdAM
Clinical trials save lives, so why do so few patients participate? A recent study indicates cost is a major ba... connection.asco.org/magazine/socie… @ASCO #clinicaltrials
6 Dec 2017               
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Charles Weijer @charlesweijer
Congratulations to #Dean #Fergusson @OttawaHospital on this groundbreaking trial. #Soproud to be working with him on our #ethics of #pragmatic #RCTs project. #pRCTethics @SG_Nicholls @GrimshawJeremy @MarionKCampbell @SpencerPHey @coryegoldstein
The Ottawa Hospital @OttawaHospital
Blood transfusions in heart surgery: global study sets new standard bit.ly/2AfC3j4 @CIHR_IRSC #onHWS
6 Dec 2017               
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Stuart Nicholls @SG_Nicholls
My week on Twitter 🎉: 11 Mentions, 851 Mention Reach, 25 Likes, 7 Retweets, 11.7K Retweet Reach. See yours with sumall.com/performancetwe…
7 Dec 2017               
Retweeted by SG_Nicholls
Paul Glasziou @PaulGlasziou
Yes - Our 2103 @PLOSMedicine article looked at disease creep in 14 conditions, with their justifications and COIs
Stuart Nicholls @SG_Nicholls
@PaulGlasziou This slippage also happened with 'at risk of overweight' becoming 'overweight'; Are there other examples of such definition creep and analysis of the processes that facilitate this?
6 Dec 2017               
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@Risk_ISSP @Risk_ISSP
The @Risk_ISSP @uOttawa project has been mentioned by @GenomeCanada in their latest press release: New projects to explore societal implications of genomics research @uOttawaMedia @MonicaGattinger

genomecanada.ca/en/news-and-ev…
6 Dec 2017               
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NIH Collaboratory @Collaboratory1
.@GregSimonKPWHRI answers the question: What is a #pragmatictrial? Watch the video & Greg’s @PlayDoh skills! @KPWaResearch bit.ly/2zQAyUA
6 Dec 2017               
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Scott Burris @scottburrisphlr
Interesting new sudy explores moral foundations theory and vaccination: nature.com/articles/s4156… Association of moral values with vaccine hesitancy. For more, check out our webinar series on crafting richer public health messages networkforphl.org/webinars/2017/…
5 Dec 2017               
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Mary Dixon-Woods @MaryDixonWoods
Systematic review is not a neutral process independent of reviewers' expertise and interests, says study of systematic reviews of mammography screening …maticreviewsjournal.biomedcentral.com/articles/10.11…
3 Dec 2017               
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Robyn Tamblyn @RobynTamblyn
FUNDING OPPORTUNITY: Health System Impact Fellowships for Doctoral Trainees and Post-Doctoral Fellows! Apply now: bit.ly/2klREXh #CIHR_ImpactFellows @CIHR_IRSC
5 Dec 2017               
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Alex Munter @AlexMunter_
Welcome, Michelle Quinlan, new #Family-Centred Research Specialist. Long-time @CHEOhospital parent to find ways for patients+families to help drive #research.
#onHWS #patientengagement
5 Dec 2017               
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Stuart Nicholls @SG_Nicholls
Example of how values and evidence are intertwined. See our paper "The need for ethics as well as evidence in evidence-based medicine" jclinepi.com/article/S0895-… @biomedethics @qmulbioethics
Stuart Nicholls @SG_Nicholls
"Although both groups followed similar transparent methods including disclosing COI, considering patients' values and preferences and using systematic methods to search for and summarize evidence, they reached different conclusions." jclinepi.com/article/S0895-…
5 Dec 2017               
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Stuart Nicholls @SG_Nicholls
"Although both groups followed similar transparent methods including disclosing COI, considering patients' values and preferences and using systematic methods to search for and summarize evidence, they reached different conclusions." jclinepi.com/article/S0895-…
5 Dec 2017               
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Ulrike Felt @Ulrike_Felt
I am looking for a PhD student wanting to working with me at the STS Department in Vienna. Have a look at sts.univie.ac.at/einzelansicht-….
5 Dec 2017               
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Jeremy Grimshaw #FBPE @GrimshawJeremy
#DIscience17 - do psychological theories distinguish between implementation and de-implementation? Come to poster 136 to find out - presenting the work of my wonderful colleague @andreapatey @TOH_CIR
5 Dec 2017               
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Stuart Nicholls @SG_Nicholls
Controversy and debate on clinical genomics sequencing by @BJWilson059 @FionaAliceMill jclinepi.com/article/S0895-… @biomedethics @annekeluc
5 Dec 2017               
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Charles Weijer @charlesweijer
#Quoteoftheday Thx to @DogICUma
5 Dec 2017               
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ImpSci @ImplementSci
Evidence use in decision-making on introducing innovations: a systematic scoping review …plementationscience.biomedcentral.com/articles/10.11… #impsci
5 Dec 2017               
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Charles Weijer @charlesweijer
#Journal #editors should publicly post #litigation threats to counter #libelchill, argues @TrudoLemmens and colleagues. #publication #ethics #research #bias @CaulfieldTim @LeighGTurner
journals.plos.org/plosmedicine/a…
5 Dec 2017               
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Mary Dixon-Woods @MaryDixonWoods
Fascinating paper about the impact of a performance dashboard on maternal /neonatal outcomes: associated with improvement on some but not all indicators of quality. qualitysafety.bmj.com/content/early/…
4 Dec 2017               
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Natalie Brender @NatalieBrender
I can't apply for these positions because of nepotism & geography--but if you want to do meaningful global health work in Toronto, it doesn't get any better than PIH Canada.
PIH Canada @PIH_Canada
We're growing! Partners In Health Canada is on the hunt for a Snr. Manager of Programs and Development, an Annual Giving Manager, & a Development Coordinator. Please share widely! pihcanada.org/careers/ #GlobalHealth #NFPJobs #Toronto
4 Dec 2017               
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PHE Screening @PHE_Screening
In 2016-17 NHS #screening programmes carried out millions of screening tests and identified 460,000 people who needed further investigation – check out PHE Screening’s latest national report for more info: bit.ly/2k4mCTL
4 Dec 2017               
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NCI_ImplSci @NCI_ImplSci
Great plenary led by @GrimshawJeremy focusing on what minimum level of evidence is (or isn't?) #impsci #DIScience17 certainly meeting the #MotivationMonday call to action
4 Dec 2017               
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CIHR @CIHR_IRSC
1/3 We are pleased to announce the launch of a revised Institute Advisory Board (IAB) model ow.ly/5TXN30gZY5O
4 Dec 2017               
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Genetic Engineering & Society Center, NCSU @GESCenterNCSU
For those doing research around #Ethics & Responsible Innovation in #STEM fields, consider submitting a poster abstract to present at workshop to be held at @NCState in March 2018.
More info → research.ncsu.edu/ges/events/cce…
*Please share within your networks*
4 Dec 2017               
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Stuart Nicholls @SG_Nicholls
Our biggest fans this week: @anetto, @GraemeLaurie, @EmTumilty. Thank you! via sumall.com/thankyou?utm_s…
4 Dec 2017               
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Jeremy Grimshaw #FBPE @GrimshawJeremy
Amazing resource - congratulations! @vawelch @HowardNWhite @campbellreviews
McMasterHealthForum @McMasterForum
We're excited to launch the beta version of Social Systems Evidence to better support policymakers, stakeholders and researchers who want to access the best available research evidence in a timely manner ow.ly/j3Gn30gVFxC #socialsystems #SDGs
3 Dec 2017               
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Shannon Kelly @itsshannon
Cool (but it’s a shame the call details are behind a paywall)!
The Lancet @TheLancet
Women in science, medicine & global health—call for papers for planned themed issue coming soon. Help us identify the best evidence to inform change. Join #LancetWomen Tues 5 Dec, 1700 h GMT/1200 h EST bit.ly/2zTYcTW
2 Dec 2017               
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Charles Weijer @charlesweijer
US #NIH encourages researchers to #publish in reputable #journals. #publication #ethics
grants.nih.gov/grants/guide/n…
2 Dec 2017               
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Monica Gattinger @MonicaGattinger
Thanks @SSHRC_CRSH @GenomeCanada & @ontariogenomics for funding @ISSP_uOttawa’s @Risk_ISSP project. Researchers incl @SG_Nicholls @GESCenterNCSU’s Jennifer Kuzma @Scott_Findlay1 @S_Fast_ @DJ_Pare @RAuOttawa @erickUdeM & many more! Thx also to partners @CNSC_CCSN @CPHA_ACSP & CNL
2 Dec 2017               
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Hilda Bastian @hildabast
No wonder research ethics committees (IRBs) come to such different decisions: studies of minutes show major inconsistency in what they even discuss bmcmedethics.biomedcentral.com/articles/10.11…
30 Nov 2017               
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James Webbe @COIN_neoepoch
ctrc.liv.ac.uk/DelphiManager/…
Link to the final Delphi survey-last day today to tell us which neonatal outcomes YOU think should be measured in research
30 Nov 2017               
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David Nunan @dnunan79
Due to popular demand - our “Top ten papers for EBM” is now free via @BMJ_EBM
ebm.bmj.com/content/22/6/2…

Power to the people.
David Nunan @dnunan79
Starting your EBM journey? Check this out:
Ten essential papers for the practice of evidence-based medicine ebm.bmj.com/content/early/… @BMJ_EBM
30 Nov 2017               
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Trisha Greenhalgh #FBPE @trishgreenhalgh
12 years since we demonstrated that overly rational database searche strategies are less efficient than fuzzy ones.
1 Dec 2017               
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Christian Burks @scienega
5 projects -- @pachowwhite, @David_Di_Zhang, @MonicaGattinger, @dmsecko and #MichelDorval on societal implications of genomics research -- funded as a @SSHRC_CRSH and @GenomeCanada joint bit.ly/2AtPVWB @GenomeBC @GenomePrairie @ontariogenomics @GenomeQuebec @ScienceMin
30 Nov 2017               
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Paul Glasziou @PaulGlasziou
3 Post-doc positions at Centre for Research in Evidence-Based Practice - call for expressions of interest: bond.edu.au/job/49764/post…
1 Dec 2017               
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Alex John London @AlexJohnLondon
Excellent opportunity to work at a top place with fun/smart people on on important topic. #bioethics #researchethics
PORTAL @ Harvard Med @PORTAL_Research
Interested in working with @akesselheim, @AmeetSarpatwari and the growing @PORTAL_Research team on projects related to pharmaceutical policy and law?

Consider our PORTAL fellowship! More information here: goo.gl/QXx6mM
1 Dec 2017               
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Lauren Kelly, Ph.D. @PharmaLauren
@SG_Nicholls @AlexJohnLondon Excellent! But I cant seem to get access to the editorial @AlexJohnLondon. Would be forever grateful if someone sent it my way 😀
30 Nov 2017 in reply to SG_Nicholls               
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Stuart Nicholls @SG_Nicholls
You wait for papers on adaptive trial design (ok, not really) and then two come along at once. I'll be reading this alongside the recent paper by @AlexJohnLondon jme.bmj.com/content/early/…
30 Nov 2017               
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Jennifer Raff @JenniferRaff
Oh god, no. People, I have a Ph.D. in genetics and I still went to a genetic counselor for my pregnancy. Personal ancestry tests are NOT a substitute for medical experts.
30 Nov 2017               
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Dave Borasky @DaveBorasky
In the year that the Nuremburg Code turns 70 the US Army will start providing medical care to chem warfare research volunteers army.mil/article/196866
30 Nov 2017               
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Harlan Krumholz @hmkyale
If we are going to caveat all observational comparative effectiveness studies...should we be doing them when randomization possible. I thought @PCORI should focus almost exclusively on pragmatic #RCTs for this reason. If you have resources, this is where best placed.
Sunil V. Rao @SVRaoMD
Observational data that is consistent w/our biases: “definitive real world data!”

Observational data that goes against our biases: “fatally confounded!”
28 Nov 2017               
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Amy Rogers @dramyrogers
Pragmatic comparative effectiveness trials on a shoestring budget? Sounds like my kind of study.
Prof Darrel Francis [cardio logically speaking] @ProfDFrancis
Yup. Whenever anyone says "comparative effectiveness study" to me, I say "ah, yes, an RCT, yes?"

As Harlan says, only we can lock trials onto questions we as Drs/patients REALLY care about.

Instead of "how much funding can we get", ask "how little can we do it for, if we focus" twitter.com/hmkyale/status…
30 Nov 2017               
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Bristol Uni CEM @BristolEthics
We are offering a new 2-day training course in empirical bioethics. One of a kind, with some great speakers lined up. bristol.ac.uk/population-hea…
29 Nov 2017               
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Stuart Nicholls @SG_Nicholls
My week on Twitter 🎉: 10 Mentions, 603 Mention Reach, 23 Likes, 7 Retweets, 6.25K Retweet Reach. See yours with sumall.com/performancetwe…
30 Nov 2017               
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Alex Munter @AlexMunter_
Thank you, Sophie Grégoire-Trudeau, for joining Team @CHEOhospital today as we help launch new Social #Pediatrics program in Vanier: cheo.on.ca/en/newsroom?ne… #ottnews #cdnhealth
29 Nov 2017               
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CIR @TOH_CIR
#CIRSpotlight on @GrimshawJeremy: general agreement that designing an intervention for individual-level healthcare professional behaviour change includes identifying barriers, selecting intervention components, using theory, and engaging end-users link.springer.com/article/10.118…
29 Nov 2017               
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Cory E. Goldstein @coryegoldstein
Panel with @charlesweijer, @riekevdgraaf, @phaikyeong, Roger Lewis, and Patricia Saidon (chaired by Katherine Littler) discussing novel #trial designs, current #guidelines, and gaps that require further specification and solutions #GFBR2017 @wellcometrust @gatesfoundation
29 Nov 2017               
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Charles Weijer @charlesweijer
Cristina Torres highlights the importance of current #ethical #principles and the need for investment in ethics #capacity #building at #GFBR2017. @wellcometrust @gatesfoundation
29 Nov 2017               
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IME @IMEweb
Bursaries for @ICCEC2018 Announced. 3 categories available: UK Undergrads and FY's; UK Postgrads and Doctors in training; Overseas Doctors and Bioethicists. All information at iccec2018.org/registration/
29 Nov 2017               
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Charles Weijer @charlesweijer
Carla Saenz @pahowho reports that #innovative #RCT designs are challenging in part due to the lack of local expertise. Problem for #REC review. #GFBR2017 @wellcometrust @gatesfoundation
29 Nov 2017               
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Brian Alexander @xelamb
Brilliant @AlexJohnLondon essay on adaptive trial ethics. Come for the RAR, stay for a stellar equipoise review. #APT #bayes jme.bmj.com/content/early/…
27 Nov 2017               
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Brenda J Wilson @BJWilson059
But in the absence of clinical utility, purchasing ‘precision’ genomics may have more impact on wallet than health. May even cause net harm. @Genioz_study @bronwynterrill @SG_Nicholls
Saskia Sanderson @SCSanderson
.@RobertCGreen: In the absence of evidence generation of clinical utility, you are left with "precision commerce". This has the potential to exacerbate health disparities because then only the wealthy purchase. #genomics #phgconf17
29 Nov 2017               
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Paul Lacaze @PaulLacaze
Agreed
Saskia Sanderson @SCSanderson
.@RobertCGreen: In the absence of evidence generation of clinical utility, you are left with "precision commerce". This has the potential to exacerbate health disparities because then only the wealthy purchase. #genomics #phgconf17
29 Nov 2017               
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Alies Maybee @amaybee
I am on some of these groups as a PFA and they don't talk or even know about each other so not seeing this as a "network". @anetto @NancyLefebre
Annette McKinnon @anetto
To be a real network the members of the outer circles also need to be communicating - a patient network, not just an engagement network of unconnected groups. #ONhealth twitter.com/NancyLefebre/s…
28 Nov 2017               
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Colleen M. Flood @ColleenFlood2
I am looking for talented graduate students in law at the Masters and Doctoral level to work on health law and policy topics and can offer scholarships of up to $10 k per annum. Please email me with your cv and statement of interest: healthlaw@uottawa.ca
28 Nov 2017               
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Eddy Nason @EddyNason
From @PCORI - great resource. Pleasee share widely. @OSSUtweets @BeACCoN_SPOR @AbSPORU_PEP @_DiabetesAction @ChildBrightNet
28 Nov 2017               
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Stuart Nicholls @SG_Nicholls
RT @charlesweijer: Most #steppedwedge #RCTs to date are NOT government policies slated for rollout, says @karlahemming. #GFBR2017 @wellcometrust @gatesfoundation
28 Nov 2017               
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Anant Bhan @AnantBhan
Few hours into #gfbr2017 and we have an engaged audience. Lots of interest in exploring the ethics of innovative designs such as CRTs, including step wedge designs
28 Nov 2017               
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Charles Weijer @charlesweijer
#RECs are all over the map as to whether #steppedwedge #RCTs need to be reviewed. #Guidance urgently needed, says @karlahemming at #GFBR2017. @wellcometrust @gatesfoundation
28 Nov 2017               
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Charles Weijer @charlesweijer
@wellcometrust @gatesfoundation To what extent should such trials involve #delayed #consent or a #waiver of #consent? #GFBR2017
28 Nov 2017 in reply to charlesweijer               
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Charles Weijer @charlesweijer
Only half of published #steppedwedge #RCTs report research ethics commitee #REC review says @karlahemming at #GFBR2017. @gatesfoundation @wellcometrust
28 Nov 2017               
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Charles Weijer @charlesweijer
Should we use #adaptive platform #trials to evaluate treatments for #critically ill #children? Yes, says Srinivas Murthy. #GFBR2017 @wellcometrust @gatesfoundation
28 Nov 2017               
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Cory E. Goldstein @coryegoldstein
@riekevdgraaf introducing our second theme at the #GFBR2017 meeting: stepped-wedge #trial designs @wellcometrust @gatesfoundation
28 Nov 2017 in reply to riekevdgraaf               
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Alex Munter @AlexMunter_
"We are currently giving money to commercial landlords, which we would rather be spending on the direct delivery of service": on its very last day of publication, @MetroOttawa profiles @CHEOhospital #1door4care campaign:
metronews.ca/news/ottawa/20…
#ottnews #Onpoli
28 Nov 2017               
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Cory E. Goldstein @coryegoldstein
Guillermo Ambrosio and @karlahemming present the #steppedwedge #cluster #RCT ¡Que Vivan las Madres! and the associated #ethical issues #GFBR2017
28 Nov 2017               
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Cory E. Goldstein @coryegoldstein
Dr. Choko presenting lessons from PASTAL: an adaptive #cluster #RCT raises 4 #ethical issues #GFBR2017 @wellcometrust @gatesfoundation
28 Nov 2017               
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Cory E. Goldstein @coryegoldstein
Srinivas Murthy asks, "How can we build the adaptive nature of the trial into the informed consent process?" #GFBR2017
28 Nov 2017               
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Cory E. Goldstein @coryegoldstein
Dr. Roshandel discussing #ethical issues in the PolyIran study: incl. cluster justification, informed consent, current practices and post-trial provisions #GFBR2017 @wellcometrust @gatesfoundation
28 Nov 2017               
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Cory E. Goldstein @coryegoldstein
Nick Day covering the overarching questions of #GFBR2017 meeting
28 Nov 2017               
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Ainsley Newson @biomedethics
FUNDED study for an MPhil (very rare!) in #ELSI #genomics at @HealthLawQUT with @B_J_Bennett See below for details
28 Nov 2017               
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Charles Weijer @charlesweijer
What determines activities requiring #REC #review? Is #generalizability the right concept, asks @michaelethox? Systematic investigation/methods to produce understanding may be more useful. #GFBR2017 @wellcometrust @gatesfoundation
28 Nov 2017               
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